Shahid Sadoughi University of Medical Sciences Applied Health Information Technology 2717-3631 1 1 2020 11 01 Designing and Evaluating a Decision Support System on Childhood Leukemia to Improve Medication Management 1 10 89 10.18502/ahit.v1i1.5253 EN Leila Shahmoradi Ph.D. in Health Information Management, Halal Research Center of IRI, FDA, Tehran, Iran. Department of Health Information Management, School of Allied-Health, Tehran University of Medical Sciences, Tehran, Iran. Asieh Salimi M.Sc. in Health Information Technology, Department of Health Information Management, School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran. 0000-0002-5038-3332 Niloofar Mohammadzadeh Ph.D. in Health Information Management, Department of Health Information Management, School of Allied-Health, Tehran University of Medical Sciences, Tehran, Iran. Marsa Gholamzadeh Ph.D. in Medical Informatics, Department of Health Information Management, School of Allied Medical Sciences, Tehran University of Medical Sciences; Tehran, Iran. Journal Article 2020 03 06 <strong>Aim</strong>: To design, develop, and evaluate a clinical decision support system (CDSS) to decrease the adverse effects of treatment in Childhood Leukemia.<br /> <strong>Method</strong>: To achieve high accuracy, a knowledge base CDSS was designed based on the viewpoints provided by experts and clinical references. The system has the capability of medical report documentation, drug prescription, dosage determination, and displaying patients’ medical history. It is also able to eliminate the problems caused by prescription and drug dosage errors by considering the patient’s status.<br /> <strong>Results</strong>: By documenting the patients’ medical report, the system can provide comprehensive information and precise recommendations about the future readmission and drug dosage accuracy. The system achieved 94.5% sensitivity, 93% accuracy, and 80% specificity in the evaluation phase.<br /> <strong>Conclusion</strong>: Application of such systems in the process of prescribing drugs can improve the quality of patient care by reducing the probability of pharmaceutical errors. https://ahit.ssu.ac.ir/article_89_b964c1e091035bd88badac0d80057650.pdf